Akt (PKB, or RAC (Related to PKA and PKC), is the cellular homologue of the viral oncoprotein v-Akt.
Akt is a serine / threonine kinase that consists of an N-terminal PH domain, a kinase domain and a C-terminal domian similar to that of the PKC family.
Akt alpha contains 480 amino acids, and can be activated by receptor tyrosine kinases through the PI 3-kinase pathway.
Akt has been shown to suppress apoptosis.
Recent study suggests that Akt may also be part of the NF-kB activation pathway.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage, store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS containing 0.09% sodium azide and 40% glycerol.
