Located in the nerve fibers in the central and peripheral nervous system, VIP is probably acting as a neurotransmitter.
The Verner-Morrison or Water Diarrhea Hypokalemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors.
VIP-producing tumors are usually neuroblastomas or endocrine tumors in the pancreas.
The localization of the antigen is extracellular and cytoplasmic.
Applications:Suitable for use in Immunohistochemistry.
Other applications have not been tested.
Recommended Dilution:Immunohistochemistry (Frozen and Paraffin sections): 1:2500-1:5000 using PAP, or 1:1500-1:3000 using FITC with overnight incubation at 2-8°C
Optimal dilutions to be determined by the researcher.
Positive Control:Formalin-fixed paraffin sections of feline ileum.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：50ul
Host：rabbit
Source Antibody：porcine
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.
Specificity：Recognizes porcine VIP. Absorption with 10-100ug immunogen per ml diluted antiserum abolishes the staining, while PHI, secretin, glucagon, GIP, and CCK do not. Species Crossreactivity: Fish and most mammals including human, feline and rat.
