The LDL receptor (160kD mature or glycosylated receptor; 120kD precursor or unglycosylated receptor) plays a key role in cellular cholesterol homeostasis.
Applications:Suitable for use in Flow Cytometry, Western Blot and Receptor binding studies.
Other applications have not been tested.
Recommended Dilutions:Flow Cytometry: 1:10Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：250ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography
Form：Supplied as a liquid in PBS, pH 7.4, with penicillin/streptomycin for antibiotic protection. Labeled with Biotin.
Specificity：Recognizes human LDLR. Recognizes the 160kD band of LDLR and a 120kD band of the LDLR precursor from fibroblasts, hepatocytes, and monocytic cells cultured in the presence of lipoprotein- deficient serum. Does not inhibit binding of LDL.
Isotype：IgG
Calc Applications Abbrev：FC WB
Calc Crossreactivity：Hu
Immunogen：Specific synthetic peptide (sequence not conserved in VLDL receptor and LRP) of the LDL receptor extracellular domain (epitope between aa184-195, the linker region between repeats 4 and 5)
