84-1062-07　NT-4,5 (Neurotrophin 4,5, NTF5) 500ug　N6000-25C

特徴

• NT-4 Propeptide (neurotrophin-4/5) is a 27kD, secreted, glycosylated neuronal polypeptide that belongs to the NGF-b family of neurotrophic factors.
• It is synthesized as a proform that contains a 9kD, 56aa proregion (aa25-80) and a 130aa mature segment.
• The mature molecule forms both nondisulfide linked heterodimers (with NGF) and homodimers.
• It is unclear if 186aa NT-4 Propeptide dimerizes, but this might be anticipated.
• Proneurotrophins are believed to activate NGFR and sortilin complexes and neurotrophin proregions regulate neurotrophin maturation.
• Over aa25-80, human NT-4 Propeptide is 89% and 91% aa identical to mouse and canine NT-4 Propeptide, respectively.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Recommended Secondary Antibodies:I1906: IgY, Chicken Pab Rb xCh I1906-10: IgY, Chicken (HRP) Rb xCh I1906-12: IgY, Chicken (FITC) Rb xCh I1906-14: IgY, Chicken (AP) Rb xChI1906-01: IgY, (HRP) Gt xCh
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.