FABP is a plasma marker of acute myocardial infarction (AMI).
The plasma kinetics of FABP (15kD) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours.
The concentration of FABP in the skeletal muscle is 20 times lower than in cardiac tissue (for myoglobin the same content for cardiac and skeletal tissue), making FABP cardiac-specific cf.
myoglobin.
This makes FABP a useful biochemical marker for the early assessment or exclusion of AMI.
FABP also appears a useful plasma marker for the estimation of myocardial infarct size.
Applications:The product can be used at 1:1000 to 1:5000 for both ELISA and immunoblot testing.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%).
Store at -20°C or colder.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:500ug
Host:chicken
Source Antibody:human
Grade:Purified
Purity:Purified
Form:Supplied as a liquid in PBS, pH 7.2.
Specificity:Binds specifically to a single band or double bands at about 15KD in various fat cell lysates from human, mouse and rat.
Isotype:IgY
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Adipocyte Fatty Acid Binding Protein mixed peptides (FDEVTADDRKVK and KWDGKSTTIKRK)