Stomatin-like protein 2 (STOML2) is a member of the stomatin superfamily and is a widely expressed mitochondrial inner membrane protein.
It acts as an oncogenic-related protein and is found to be up-regulated in multi-cancers.
STOML2 has a role and clinical significance in gastric adenocarcinoma and gallbladder cancer (GBC).
Increased expression of STOML2 may lead to unfavorable prognosis for gastric adenocarcinoma patients.
STOML2 may play an important role in human GBC tumorigenesis and may serve as a novel prognostic marker in human GBC.
It interacts with prohibitin-1 and -2 and binds to the mitochondrial membrane phospholipid cardiolipin.
The up-regulation of this gene expression increases cardiolipin content, the formation of metabolically active mitochondrial membranes and also induces mitochondrial biogenesis.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500, tissue or cell staining 1:200
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：chicken
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Specificity：Recognizes human Stomatin (EPB72)-like 2. Species Crossreactivity: mouse and rat.
Isotype：IgY
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa171-356 of Stomatin (EPB72)-like 2
