Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy.
Progesterone receptor, a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone.
The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB.
Although PRA and PRB share several structural domains, they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:500Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibodies:I1906-10: IgY, Chicken-HRP Rb x Ch I1906-12: IgY, Chicken-FITC Rb x Ch I1906-14: IgY, Chicken-AP Rb x Ch
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:chicken
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Specificity:Recognizes human Progesterone Receptor.
Isotype:IgY
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to aa61-350 of human Progesterone Receptor.