84-1060-79　［取扱停止］Nucleolar Protein Family A, Member 1 (GAR1 Protein, NOLA1) 50ug　N6939-61

特徴

• The gene that encodes this protein is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family.
• snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA.
• The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins.
• These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus.
• Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted.
• These four H/ACA snoRNP proteins are also components of the telomerase complex.
• The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:250Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage, store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.