84-1060-32　［取扱停止］Fibronectin 5mg　F4215-01G

特徴

• The extracellular matrix is a complex network of secreted (glyco)proteins situated in between cells of particular types of tissue.
• The relative amounts of the different types of matrix macromolecules and the way in which they are organized in the extracellular matrix vary between different tissues.
• For example, connective tissues have extensive extracellular matrices in which fibrous polymers, especially collagen, are present.
• In contrast, in epithelial tissues the extracellular matrix consists only of a thin mat called the basal lamina, which underlies the epithelial cell sheet.
• Cells located in the extracellular matrix produce matrix constituents and control the organization of these matrix components.
• The main components of the extracellular matrix are proteoglycans (e.g.
• aggrecan, perlecan and syndecan) and fibrous proteins (e.g.
• collagen, elastin, fibronectin and laminin).
• The extracellular matrix, next to being a scaffold to support cells in a particular tissue, also plays a role in the regulation of processes such as proliferation, differentiation, adhesion and locomotion of these cells.
• Applications:Suitable for use in ELISA, Inhibition.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:10,000Inhibition: 1:100 completely inhibits binding of Staphylococcus aureus to immobilized fibronectin N-terminal domain (coating concentration: 20ug/ml)
• Optimum dilutions to be determined by researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.