Chemokine receptors are specialized proteins that function at the surface of cells, and enable chemokines to trigger internal cellular processes.
Chemokines and their receptors play a pivotal role in lymphocyte trafficking, recruiting and recirculation.
Chemokines act through seven transmembrane G protein-coupled receptors.
The chemokine system is increasingly recognized to play an important role in lymphocyte biology.
Application(s):ELISA: 1:100,000 Western Blotting: 1:1,000 Immunohistochemistry: 1:250 Flow Cytometry: 1:200
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage, store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:goat
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.09% sodium azide before the addition of 40% glycerol.
Specificity:Peptide sequence is < 50% identical to other mouse chemokine receptors in this region. Recognizes mouse CCR9 and Crossreacts to human CCR9 with approximately 50% less titer. Crossreacts with mouse and human.
Isotype:IgG
Calc Applications Abbrev:E FC IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide IPGMFDDFSYDSTASTDDYMNLNFSSFF corresponding to aa 10-37 of mouse CCR9.