Chemokine receptors are specialized proteins that function at the surface of cells, and enable chemokines to trigger internal cellular processes.
Chemokines and their receptors play a pivotal role in lymphocyte trafficking, recruiting and recirculation.
Chemokines act through seven transmembrane G protein-coupled receptors.
The chemokine system is increasingly recognized to play an important role in lymphocyte biology.
Applications:Suitable for use in Flow Cytometry, ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:25,000 Western Blot: 1:500 Immunohistochemistry: 1:250 Flow Cytometry: 2ul labels 10e6 cells in 100ul Optimal dilution determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.09% sodium azide.
Specificity：Recognizes mouse CCR4. No crossreactivity to human CCR4.
Isotype：IgG
Calc Applications Abbrev：E FC IHC WB
Calc Crossreactivity：Mo
Immunogen：Synthetic peptide DTTQDETVYNSYYFYESMPC corresponding to amino acid residues 8-26 of mouse CC chemokine receptor CCR4. Species sequence homology: other human chemokine receptors <50%.
