84-1058-97　TLR1 (Toll Like Receptor 1) 100ug　T8050-03

特徴

• The Toll-like receptor (TLR) family in mammals are comprised of a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain.
• The TLRs could constitute an important and unrecognized component of innate immunity in humans.
• In mice, TLR1 interacts with TLR2 and coexpression of TLR1 and TLR2 enhance the NF-kappaB activation in response to a synthetic lipopeptide.
• They recognize the lipid configuration of the native mycobacterial lipoprotein as well as several triacylated lipopeptides.
• Applications:Suitable for use in Western Blot and Flow Cytometry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1-3ug/mlFlow Cytometry: 2-4ug/1x10e6 cellsOptimal dilutions to be determined by the researcher.
• Recommended Positive Control: Ramos cell lysate (87kD)
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage, store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.