Smad7 is a member of the MAD-related family of molecules.
MAD-related proteins are a recently identified family of intracellular proteins that are thought to be essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily (1).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 2-5ug/ml
Optimal dilutions to be determined by the researcher.
Recommended Positive Control:HepG2 cells
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity:Recognizes human Smad7. May cross-react with SMAD6 depending on cell or tissue-specific expression Species Crossreactivity: Mouse, rat. Species sequence homology: Canine, pufferfish, zebrafish, Xenopus, chimpanzee.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa 12-18 of human Smad7.