84-1055-43 Plasminogen Activator Inhibitor Type 1 (PAI-1) 1mg P4256-31H
特徴
- Plasminogen Activator Inhibitor 1 (PAI-1) is a glycoprotein found in plasma.
- It is implicated in the processes of angiogenesis, hemostasis, tumor metastasis, fibrionlysis, ovulation, embryonic development and inflammation.
- The elevation of PAI-1 has shown to correlate with the prognosis of many cancers including breast cancer.
- PAI-1 is activated by the glycoprotein vitronectin.
- Vitronectin binds to PAI-1 and modulates fibrinolysis and cell migration.
- This binding has proven to be an important inhibitor of the activated form of protein C (APC).
- Applications:Suitable for use in ELISA, Immunohistochemistry and Western Blot.
- Other applications not tested.
- Recommended Dilutions:Optimum dilutions to be determined by researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:1mg
- Host:rabbit
- Source Antibody:rat
- Grade:Affinity Purified
- Purity:Purified by Protein A affinity chromatography.
- Form:Supplied as a liquid in PBS, pH 6.6, 1mM EDTA.
- Specificity:Recognizes rat Plasminogen Activator Inhibitor Type 1.
- Isotype:IgG
- Calc Applications Abbrev:E IHC WB
- Calc Crossreactivity:Rt
- Immunogen:Recombinant protein corresponding to rat Plasminogen Activator Inhibitor Type 1 (PAI-1). MW: 50kD, glycosylated; 43kD, non-glycosylated.
- Shelf Life:1year
- EU Commodity Code:30021010
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