84-1053-68 β-Amyloid (1-42) 100ul A2275-74Q
特徴
- Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein.
- Beta amyloid is an extracellular filamentous protein deposit found in the brain.
- It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles.
- In man, Alzheimer’s disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain.
- Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type) and in the Guam Parkinson-Dementia complex.
- Applications: Suitable for use in Immunohistochemistry, Western Blot, ELISA.
- Used in immunohistochemical staining of Alzheimer's disease plaques.
- Recommended Dilution:Immunohistochemistry: Paraffin.
- Requires formic acid pre-treatment.
- Western Blotting: 1:500-1:1000Optimal working dilutions to be determined by researcher.
- Recommended Secondary Reagents: Sheep anti Rabbit IgG (Aff.
- Pur.): HRPRecommended Positive Control Tissue: Alzheimer's diease brain
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Serum
- Purity:Serum
- Form:Supplied as a liquid in 0.02% sodium azide.
- Specificity:Recognizes the beta amyloid (1-42) peptide that is an important factor in the pathogenesis of Alzheimer's disease.
- Isotype:IgG
- Calc Crossreactivity:Hu
- Immunogen:Antisera to Beta amyloid (1-42) were raised by repeated immunizations of rabbits with highly purified antigen.
- Shelf Life:1year
- EU Commodity Code:30021010
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