84-1052-25　BCMA (B Cell Maturation Protein) 100ug　B0807-50

特徴

• Members in the TNF superfamily regulate immune responses and induce apoptosis.
• Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL- 2, respectively.
• BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion.
• April regulates immunological and non-immunological cell growth.
• Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified).
• BCMA, like TACI, binds BAFF and April.
• BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
• Applications:Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 5ug/mlImmunohistochemistry: 5-10ug/mlImmunofluorescence: 10ug/mlOptimal dilutions to be determined by the researcher.
• Positive Controls:K562 cell lysate, U937 cell lysate, Human spleen tissue lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.