84-1043-76　Galanin Receptor 1 (GALR1) 100ul　G1043-05A

特徴

• Galanin is a 29aa C-terminally amidated (30aa, non-amidated in humans), highly conserved but unique neuroendocrine peptide originally isolated from intestine.
• The first 14aa are fully conserved in almost all species.
• Galanin is found in the brain and the gut.
• It modulates a variety of physiological processed including cognition/memory, sensory/pain processing, neurotransmitter/hormone secretion, and feeding behavior.
• Several N-terminally elongated (-7-29 and -9-29) or truncated biologically active forms of galanin have also been isolated.
• Galanin antagonists are chimeric peptides generated by linking the amino terminal portion of galanin to substance P (galantide, M15), bradykinin (M35), the neurokinin antagonist spantide (C7) or an idealized alpha helical region (M40) (see review in refs 2 by Kask et al 1995).
• Galanin mediated its biological effects by interacting with high affinity cell surface G-protein coupled receptors (GALR1-3).
• Applications:Suitable for use in ELISA.
• Western Blot, though not tested, may potentially be used as an application.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:10-1:1000,000 (Coat with 50-100ng Control Peptide/well)
• Western Blot: 1:1000-1:5,000Optimal dilutions to be determined by the researcher.
• Recommended Control Peptide:G1043-05H: Galanin Receptor 1, Mouse (GALR1) (Control Peptide)
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.