84-1042-65　Dopamine Receptor, D2R 50ul　D9016-40

特徴

• Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport.
• A family of 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses.
• DR have been classified into either the D1-like (D1, D1B, and D5) or D2-like (D2, D3, and D4).
• Dopamine D2 receptor is known to exist in the short (D2S) and the long (D2L)forms that are encoded by splice variants of a single gene and differ only by the presence of an additional 29 amino acid in the intracellular, cytoplasmic loop 3.
• D2L receptor is a 446aa, G- protein coupled, and transmembrane receptor protein.
• D2R may play a role in the coupling of the receptor to G-proteins.
• All members of this family have similar structure and contain 7 putative transmembrane domains.
• Applications:Suitable for use in ELISA.
• Western Blot, though not tested, may potentially be used as an application.
• Other applications not tested.
• Recommended Dilutions:ELISA: 1:10,000-1:50,000 Control peptide can be used to coat ELISA plates at 1ug/ml and detected with antibodiesOptimal dilutions to be determined by the researcher.
• Control Peptide:D9016-42: Dopamine Receptor, Rat, Control Peptide, D2R
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.