AQP6 (WCH3 or hKID or AQP2-like; 282 aa; 29kD; chromosome 12q13) is found only in the kidney with low water permeability.
AQP families of proteins are predicted to contain six transmembrane domains.
The N and C-terminus are predicted to be cytoplasmic.
AQP6 shows greatest homology with hMIP (48%) and hAQP-2 (52%).
It also has similarity with human MIWC (AQP4; 34%), CHIP-28 (AQP1; 38%), and GLIP (AQP3; 22%).
Applications:Suitable for use in ELISA.
Western Blot, though not tested, may potentially be used as an application.
Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:5000 using Chemiluminescence technique
ELISA: 1:10,000-1:50,000.
Coat ELISA plate with 1ug/ml control peptide
Optimal dilutions to be determined by the researcher.
Recommended Control Peptide:A3000-25D: Aquaporin 6, Human, Control Peptide (WCH3, hKID, AQP2-L)
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a liquid in PBS, 0.05% sodium azide.
Specificity：Recognizes human Aquaporin 6. Epitope recognized by this antibody is not found in human AQP6 isoform 2. No significant homology to AQP2 or any other AQPs.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide, 19aa corresponding within the carboxy terminal domain of human AQP6 (KLH). Cellular Localization: Cytoplasmic. Species Sequence Homology: rat: 47%.
