84-1040-45 [取扱停止]Angiotensin II Type 2 Receptor (AT2) 100ug A2295-07S

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特徴

  • Angiotensin II mediates its action by interacting with membrane receptor, Angiotensin II type 1 receptors.
  • The signal is transmitted via G-proteins that activate a phosphatidylinositol- calcium second messenger system.
  • ATII receptors are integral membrane proteins of approx.
  • 359-363aa and predicted to contain at least 7 transmembrane domains.
  • The N and C-terminus are predicted to extracellular and cytoplasmic, respectively.
  • Three isoforms of ATII receptors have been cloned.
  • In rat, type 1a (359aa) is expressed in the liver kidney, aorta, lung, uterus, ovary, spleen, heart, adrenal and vascular smooth muscles.
  • Rat Type 1b (also known as AT3; 359aa) is found in liver, kidney, and aorta.
  • Type 1c (177aa) has been detected in brain, kidney, liver, spleen and lung.
  • Applications:Suitable for use in ELISA.
  • Western Blot, though not tested, may potentially be used as an application.
  • Other applications not tested.
  • Recommended Dilution:Western Blot: 1-10ug/ml (ECL).
  • Detects ~45kD band
  • ELISA: 1:10,000-1:100,000 using 50-100ng of A2295-07U control peptide/well
  • Optimal dilutions to be determined by the researcher.
  • Storage and Stability:May be stored at 4°C for short-term only.
  • For long-term storage, aliquot and store at -20°C.
  • Aliquots are stable for at least 12 months at -20°C.
  • For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Further dilutions can be made in assay buffer.

仕様

  • Size:100ug
  • Host:rabbit
  • Source Antibody:human
  • Grade:Affinity Purified
  • Purity:Purified by immunoaffinity chromatography.
  • Form:Supplied as a liquid in PBS, pH 7.2, 0.1% BSA, 40% glycerol.
  • Specificity:Recognizes human AT2 receptor. No sequence homology with other G-protein coupled receptors.
  • Isotype:IgG
  • Calc Applications Abbrev:E
  • Calc Crossreactivity:Hu
  • Immunogen:Synthetic peptide consisting of 18aa sequence mapping near the C-terminus of human AT2 (KLH). Species Sequence Homology: Rabbit: 100%; rat: 88%; mouse: 83%.
  • Shelf Life:1year
  • EU Commodity Code:30021010
  • この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
  • 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
  • 【試薬に関するお問合せ】
  • アズワン株式会社 試薬・プロセス材料グループ
  • TEL:06-6447-8641
  • FAX:06-6447-8642
  • E-mail:[email protected]
アズワン品番
84-1040-45
型番
A2295-07S
入り数
1個
標準価格
190,000円(税抜)
WEB価格
取扱停止
アズワン在庫 [?]
数量

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