84-1038-38　Somatostatin Receptor Type 2 (SSTr2) 100ul　S5331-46

特徴

• Somatostatin is a tetradecapeptide that is widely distributed in the body.
• It acts on multiple organs in the body and also functions as a neuropeptide affecting electrical activity of neurons.
• Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, cerebrum and kidney, respectively
• Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues.
• Activation of these receptors by somatostatin, which is secreted by nerve and endocrine cells, regulates the secretion of insulin, glucagon and growth hormone, neuronal excitability in both the brain and the peripheral nervous system, and cell growth.
• Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.
• Somatostatin was originally isolated from the hypothalamus and characterized by its ability to inhibit release of growth hormone from the pituitary gland.
• It exists in two forms, somatostatin-14, composed of 14 amino acids and somatostatin-28, a prohormone composed of 28 residues.
• Applications:Suitable for use in ELISA, Immunohistochemistry, Immunofluorescence and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:100-1:1000 (ECL) (75-85kD band; may see smaller MW bands as well)Immunofluorescence 1:100-1:250Immunohistochemistry: ParrafinOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.