Peripherin is a Class III intermediate filament subunit found in both the peripheral and central nervous systems, though it is concentrated, as its name suggests, in the neurons of peripheral ganglia and their processes.
Antibodies to peripherin can be used in identifying, classifying, and studying neurons in the nervous system.
Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig’s disease and some neuronally derived tumors.
Peripherin is also a major component of the cytoskeleton of PC12 cells, widely used model system for studies of neuronal differentiation.
Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes.
Peripherin is not related to peripherin-RDS, a photoreceptor protein associated with retinal degeneration and blindness.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：rat
Grade：Serum
Purity：Serum
Form：Supplied as a liquid, 0.01% sodium azide
Specificity：Recognizes rat peripherin, showing no crossreactivity with other Class III intermediate filament proteins. Species crossreactivity: Human and all other mammalian species to date. Results on avian tissues are however not conclusive
