Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H.
NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa.
Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture.
NF-L antibody can also be useful in the diagnostics of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig’s disease or Alzheimerís disease.
Applications:Suitable for use in Immunohistochemistry and Western Blot.
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:porcine
Grade:Serum
Purity:Serum
Form:Supplied as a liquid.
Specificity:Recognizes the light neurofilament subunit (~68kD). Species crossreactivity: Human, bovine, porcine, mouse, rat, avian. Should crossreact with most other mammals.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Av Bo Hu Mo Po Rt
Immunogen:Native NF-L purified from porcine spinal cord