The Ah Receptor belongs to a family of proteins comprised of its dimerization partner ARNT (HIF-1 Beta) and the Drosophila proteins PER and SIM.
All of these proteins share an N-terminal sequence of ~200aa termed the PAS domain.
This receptor, found in a variety of tissues, binds to a specific DNA enhancer sequence and initiates transcription of the mRNA for the cytochrome P-450 (CYPIA1) gene.
Applications:Suitable for use in ELISA, Western Blot and Gel Super Shift Assays.
Other applications not tested.
Recommended Dilutions:Gel Super Shift Assays: 4ul to a 15ul final volume of EMSA sample
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:1ml
Host:goat
Source Antibody:human
Grade:Serum
Purity:Serum
Form:Supplied as a liquid, 0.09% sodium azide
Specificity:Recognizes human Ah Receptor. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo
Immunogen:N-terminal sequence of the Ah receptor based on the Ah receptor purified from C57BL/6J mice