Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP.
Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton.
Shank1a is a splice variant of Shank1.
Applications:Suitable for use in Western Blot.
Other applications have not been tested
Recommended Dilution:Western Blot: 1:250-1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage, store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide before the addition of glycerol to 40%.
Specificity:Reacts with residues [SGPIYPGLFDIRSS] of the C terminus of the Shank1a protein.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide, aa[SGPIYPGLFDIRSS] of the C terminus of the Shank1a protein.