Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis.
Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids.
However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly.
A novel member of the human ov-serpin gene family, SERPIN B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestines.
SERPIN B12 is an inhibitor of trypsin-like serine proteinases and a new functional member of the human ov-serpin family.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:250-1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide before the addition of 40% glycerol.
Specificity：Reacts with residues 260–275 of the human SERPIN B12 protein.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide, aa260–275 of the human SERPIN B12 protein.
