The family of p21-activated protein kinases (PAKs) is composed of serine-threonine kinases whose activity is regulated by the GTPases, Rac and Cdc42.
PAKs have been implicated in the regulation of mitogen-activated protein cascades, cellular morphological and cytoskeletal changes, neurite outgrowth, and cell apoptosis.
A novel human PAK-interacting protein, hPIP1, interacts with PAK1 and inhibits the Cdc42/Rac-stimulated kinase activity suggesting that hPIP1 is a negative regulator of PAK and PAK signaling pathways.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:250-1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide before the addition of 40% glycerol.
