84-1033-63 ［取扱停止］GRIM19 (Genes Associated with Retinoid IFN Induced Mortality) 100ug G8969
特徴
- A novel gene, Genes associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene has been identified.
- Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein.
- Overexpression of GRIM-19 enhances cell death in response to IFN/RA.
- GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination.
- These data indicate that GRIM-19 is a novel cell death-regulatory molecule.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ug
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by affinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
- Specificity：Recognizes human GRIM-19.
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to aa159-172, QAETDRRTLQMLRE of human GRIM-19 protein. Species Sequence Homology: rat and mouse 85%.
- Shelf Life：1year
- EU Commodity Code：30021010
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