Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone.
It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD.
The protein has been found in osteoblasts and osteocytes.
BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells.
Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers.
Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling.
Applications:Suitable for use in ELISA and Immunocytochemistry Other applications not tested.
Recommended Dilutions:ELISA: 1:100Immunocytochemistry: 1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Serum
Purity:Neat serum
Form:Supplied as a lyophilized powder. No preservative added. Reconstitute with sterile ddH2O.
Specificity:Recognizes human Bone Sialoprotein, aa39-47.
Isotype:IgG
Calc Applications Abbrev:E IC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide from human Bone Sialoprotein (aa39-47, LKRFPVQGG).