84-1031-65　［取扱停止］Vasopressin Receptor V1a (AVR-V1a) 100ul　V2120-30

特徴

• Rat AVR-V1a receptor is a G-protein coupled membrane protein with seven transmembrane domain.
• N-terminus is predicted to be extracellular.
• Vasopressin (AVP, Arginine-8-Vasopressin), the antidiuretic hormone is cyclic nonapeptide invovled in the homeostasis of body fluid osmolality, blood volume, vascular tone, and blood pressure.
• Specific actions of AVP include inhibition of diuresis, contraction of smooth muscle, stimulation of liver glycogenesis, and modulation of ACTH release from pituitary.
• AVP belongs to the family of vasocative and mitogenic peptide invovled in normal and pathological cell growth and differentiation.
• AVP receptors are members of the G-protein coupled receptors with putative 7 transmembrane domains.
• The sizes of various AVP receptors are V1a (rat, 424 AA; human, 418 AA); V1b (rat, 421 AA; human, 424 AA); V2 (rat, 371 AA; human 371 AA).
• The N-terminus and C-terminus are predicted to be extracellular and cytoplasmic, respectively.
• Applications:Suitable for use in ELISA.
• Western Blot, though not tested, may potentially be used as an application.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:10,000-1:50,000Western Blot: 1:1000-1:5000Optimal dilutions to be determined by the researcher.
• Control Peptide:V2120-30A Vasopressin Receptor V1a Control Peptide
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage, store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.