Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors.
The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein.
The alpha- and beta-synuclein proteins are found primarily in brain tissue, where they are seen mainly in presynaptic terminals.
The gamma-synuclein protein is found primarily in the peripheral nervous system and retina, but its expression in breast tumors is a marker for tumor progression.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications have not been tested.
Recommended Dilutions: Western Blot: 1:1000Immunohistochemistry: 1:1000 on frozen and paraffin embedded tissueOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. No preservative added. Reconstitute with 50ul of sterile ddH2O.
Specificity：Recognizes human Synuclein, pan. Staining pattern overlaps alpha, beta and gamma-synuclein maps. Species crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Rt
Immunogen：Synthetic peptide corresponding to aa11-26 of human alpha, beta, and gamma (82%)-synuclein protein. The peptide was chosen so that the antibody would recognize all three forms of synuclein
