Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells.
It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular “head” regions linked by triple-helical, collagen-like, strands.
This group also includes SP-D and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells.
Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
The serum concentration is 45ng/ml in healthy individuals.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilutions:ELISA: 1:1000-1:30,000Western Blot: 1:1000-1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:bovine
Grade:Serum
Purity:Serum
Form:Supplied as a liquid. No preservative added.
Specificity:Recognzies bovine SP-A. Species Crossreactivity: sheep