84-1030-97 Orexin 2 Receptor 50ug O7505
特徴
- Several peptides associated with feeding behavior have been reported recently.
- Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (1).
- Orexin-A and Orexin-B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage.
- Prepro-orexin is an 130 aa peptide with a putative 33 aa secretory sequence, a hydrophobic core followed by residues with small polar side chains.
- The expression was detected in brain and to a small extent in testis (1).
- These neuropeptides bind and activate two closely related Orexin receptors—G protein coupled receptors (GPCRs) OX1R and OX2R.
- Applications:Suitable for use in Immunohistochemistry, Western Blot and ELISA.
- Other applications have not been tested.
- Recommended Dilution:Western Blot: 1-10ug/ml ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide per well
- Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ug
- Host:rabbit
- Source Antibody:rat
- Grade:Affinity Purified
- Purity:Purified by affinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.4, 0.1% BSA.
- Specificity:Recognizes rat Orexin 2 Receptor. Species Crossreactivity: mouse and human
- Isotype:IgG
- Calc Applications Abbrev:E IHC WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:A 19aa peptide near the C-terminus of rat OX2R.
- Shelf Life:1year
- Swiss Prot Number:P56719
- EU Commodity Code:30021010
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