84-1030-90 NT-3 (Neurotrophin 3, HDNF, NGF-2, Nerve growth factor-2) 20ug N6000-07E
特徴
- NT-3 is a neurotrophic factor structurally related to NGF, BDNF, and NT-4.
- These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures.
- NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors.
- NT-3 promotes the growth and survival of nerve and glial cells.
- The amino acid sequences of human, murine and rat NT-3 are identical.
- Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6kD polypeptide monomers (238 total amino acid residues).
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 0.5-2ug/mlImmunohistochemistry: 0.5-2ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
- Reconstitute with sterile ddH2O.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size:20ug
- Host:rabbit
- Source Antibody:mouse
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a lyophilized powder in PBS. No preservatives added. Reconstitute with sterile ddH2O.
- Specificity:Recognizes mouse Neurotrophin 3 (NT3). Does not crossreact with BDNF or NGF. Species Crossreactivity: Human, rat and chicken.
- Isotype:IgG
- Calc Applications Abbrev:IHC WB
- Calc Crossreactivity:Ch Hu Mo Rt
- Immunogen:An 11 amino acid peptide corresponding to the amino-terminal of mouse Neurotrophin 3 (NT3) coupled to BSA.
- Shelf Life:1year
- Swiss Prot Number:P20181
- EU Commodity Code:30021010
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