84-1030-75　［取扱停止］Nerve Growth Factor, beta (NGFb) 20ug　N2350-08C

特徴

• This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex.
• This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons.
• Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Also suitable for use in vivo animal studies and inhibition of biological activity in vitro.
• Other applications not tested.
• Recommended Dilutions:ELISA: 2-5ug/ml Western Blot: 0.5-2ug/mlImmunohistochemistry: 0.5-2ug/mlInhibition of biological activity in vitro: 1-2ug/mlIn vivo animal studies: neatOptimal dilutions to be determined by the researcher.
• Biological Activity:N2350-08C completely inhibits neuron survival and the outgrowth actions of mouse NGF in chicken dorsal root ganglion in vitro.
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.