Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors.
The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits.
This gene encodes the gamma 2 subunit of GABA(A) receptor.
Mutations in this gene have been associated with epilepsy and febrile seizures.
Alternative splicing of this gene results in transcript variants encoding different isoforms.
Applications:Suitable for use in Western Blot, Immunoprecipitation and ELISA.
Other applications not tested.
Recommended Dilution:Western Not: 1:500-1:1000.
Recognizes a 45-47kD protein.
Optimal dilution determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：rat
Grade：Serum
Purity：Serum
Form：Supplied as a liquid.
Specificity：Recognizes rat GABA-A receptor gamma 2 subunit. No known crossreactivity with other gamma GABA-A receptor or alpha and beta subunits. Other species have not yet been tested.
Isotype：IgG
Calc Applications Abbrev：E IP WB
Calc Crossreactivity：Rt
Immunogen：Synthetic peptide corresponding to rat GABA-A receptor gamma 2 subunit from the N-terminus.
