This gene encodes an alpha chain for one of the low abundance fibrillar collagens.
Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains.
Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen.
This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations.
Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.
Applications:Suitable for use in RIA, Immunofluorescence and ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:IgG fraction
Form:Supplied as a liquid
Specificity:Recognizes human Collagen Type V. Shows less than 0.1% reactivity with human Collagen Types I, III, and IV. C7510-55K also shows 0.1% reactivity with human Fibronectin and mouse Laminin by radioimmunoassay. Crossreactivity: Human collagen type I, II, & III: < 0.5%, Human collagen type IV: 20%, Human fibronectin, albumin, immunoglobulins: < 0.5%.
Isotype:IgG
Calc Applications Abbrev:E IF RIA
Calc Crossreactivity:Hu
Immunogen:Extracted and purified from human placenta