This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen.
Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms.
Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Applications:Suitable for use in Immunofluorescence and ELISA.
Other applications not tested.
Recommended Dilutions:ELISA: 1:3,000 ndirect immunofluorescence on cryostat sections or cultured cells: 1:20-1:40 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：500ul
Host：rabbit
Source Antibody：human
Grade：Highly Purified
Purity：Immunoglobulin fraction prepared by ammonium sulfate precipitation and chromatography on DEAE-cellulose, of antiserum cross-absorbed over immobilized human albumin, immunoglobulin and collagen types I, IV and V.
Form：Supplied as a liquid in PBS, pH 7.5, 0.1% mannitol, 0.1% dextran. No preservative added.
Specificity：Recognizes human Type III collagen. ELISA on collagen type I: 1:8000. Crossreactivity: Human collagen type I: < 10%, Human collagen type II: < 0.5%, Human collagen type III: 100%, Human collagen type IV: < 0.5% Human collagen type V: < 0.5%, Human fibronectin: < 0.5%, Human albumin: < 0.5%, Human immunoglobulin: < 0.5%
