Cholinergic systems are implicated in numerous neurologic functions.
Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease.
The protein encoded by this gene synthesizes the neurotransmitter acetylcholine.
Alternative splice variants have been found that contain alternative 5' untranslated exons.
Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein.
Applications:Immunohistochemistry: 1:1000–1:2000Western Blot
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：sheep
Source Antibody：porcine
Grade：Serum
Purity：Serum
Form：Supplied as a liquid in 0.05% sodium azide
Specificity：Recognizes Choline Acetyltransferase (ChAT). Will stain cholinergic neurons in rat, guinea-pig and rabbit central and peripheral nervous systems. Species Crossreactivity: rat, guinea pig and rabbit
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Gp Po Rb Rt
Immunogen：A 22aa peptide from porcine ChAT, coupled to KLH. The sequence is HGLFSSYRLPGHTQDTLVAQKSS- NH2
