84-1022-19　［取扱停止］Interleukin 21, IN (IL-21 IN) 100ug　I8442

特徴

• A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15.
• The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family.
• IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling.
• IL-21 and its receptor activate JAK-STAT signaling pathway.
• IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines.
• IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
• Applications:Suitable for use in Western Blotting.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:Human HL-60 and THP-1 cell lysates
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C or colder.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.