84-1021-95　Opioid Receptor, delta, CT, aa360-372 100ul　O7030-10

特徴

• The function of the delta-opioid receptors has not been determined.
• However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception.
• In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response.
• The opioid signal is transduced from receptors through G proteins to various different effectors.
• Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal.
• For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.
• Applications:Suitable for ELISA, Immunohistochemistry and Western Blot.
• Other applications have not been tested.
• Recommended Dilution:Immunohistochemistry (ABC): 1:800 Stains specific cells in various regions of PLP fixed rat brain sections known to express the delta opioid receptor
• Western Blot: 1:800; Band at ~55kD is observed using whole rat brain homogenate
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile PBS, 10mg/ml BSA.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.