The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors.
DRD2 may be linked to alcoholism and other substance-use disorders.
Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease.
Three alternatively spliced isoforms have been identified.
DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord.
ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
Applications:Suitable for use in Immunohistochemistry, Western Blot and ELISA.
Other applications not tested.
Recommended Dilutions:Immunohistochemistry: 1:5000Western Blot: 1:800Optimal dilution determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile PBS, 10mg/ml BSA.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute with 100ul sterile PBS, 10mg/ml BSA.
