This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
The most common feature of these malignancies is the restricted expression of a single light chain class.
Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Applications:Suitable for use in Immunohistochemistry.
Other applications have not been tested.
Recommended Dilution:Immunohistochemistry (Formalin/paraffin): 1:100-1:200 for 30 min at RT.
Note: Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
Optimal dilutions to be determined by the researcher.
Positive Control: Tonsil
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：500ul
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Specificity：Recognizes lambda light chains of human immunoglobulins, free lambda light chains and Bence-Jones lambda light chains (25kD). Does not crossreact with kappa light chains. Species Crossreactivity: Human, baboon, mouse and rat. Does not crossreact with canine.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Lambda light chains purified from human Bence Jones proteins. Cellular Localization: Cytoplasmic.
