The G protein family of signal transducers includes the alpha, beta, gamma subunits and the effector which are most clearly distinguished by their different alpha chains.
The family also includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein of unknown function that is abundantly expressed in brain; and transducin 1 and 2, proteins involved in retinal phototransduction.
The G proteins possess GTPase activity and are components of a complex membrane signaling system that includes membrane-bound receptors.
The system exists to modulate extracellular signals as they are transmitted into the cell.
Applications:Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunocytochemistry.
Other applications not tested.
Recommended Dilutions:ELISA (Peptide): 1:1000 Optimal dilutions to be determined by researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity：Recognizes both the large (MW ~52kD) and small (MW ~45kD) forms of Gs alpha. Does not crossreact with other G proteins. Species Crossreactivity: human, mouse
Isotype：IgG
Calc Applications Abbrev：E IC IP WB
Calc Crossreactivity：Bo Hu Mo
Immunogen：Synthetic peptide corresponding to aa385-394 RMHLRQYELL at the C-terminal region of Gs alpha, conjugated to KLH (NM_000516). Species Sequence Homology: human
