84-1015-66　Survivin, CT (TIAP, API4) 100ug　S8500

特徴

• Apoptosis, or programmed cell death, is related to many diseases, such as cancer.
• Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins.
• IAP proteins form a conserved gene family that binds to and inhibits cell death proteases.
• A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP.
• Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity.
• Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.
• Applications:Suitable for use in ELISA, Western Blot and Immunocytochemistry.
• Other applications have not been tested.
• Recommended Dilution:Western Blot: 0.5-1ug/mlImmunocytochemistry: 10ug/ml
• Optimal dilutions to be determined by the researcher.
• Positive Control:MOLT4 cell lysate
• Blocking Peptide:S8500P
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.