The CC chemokine eotaxin is a potent and specific eosinophil chemoattractant that is expressed by a variety of cell types in certain inflammatory conditions (1,2).
Some G-protein coupled chemokine receptors are also utilized as virus coreceptors for fusion and infection of cells.
The eotaxin receptor CCR3 is required for HIV-1 entry into target cells such as microglia and eotaxin inhibits the infection of HIV-1 (3,4).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
Positive Control: Recombinant protein
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Supplied as purified IgG
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes human Eotaxin. monomer and homodimer are detected at ~9 and 18kD.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Peptide corresponding to amino acids 83 to 97 of human eotaxin (1,2).