Anti-ganglioside asialo GM2 is very useful in the identification of ganglioside asialo GM2 and in immunotargeting cells expressing asialo GM2.
Several gangliosides have been found to have an elevated expression in tumor cells.
Many therapeutic treatments of tumor cells are being investigated using antibodies to target cells that express these elevated levels of gangliosides.
Lymphoma has been shown to have an increased level of asialo GM2 and passve immunization with monoclonal immunoglobulin G3 antibodies to asialo GM2 has effectively supressed tumor formation in these cells.
Asialo GM2 has been identified as a receptor for many types of bacteria including Neisseria gonorrhoeae and Haemophilus influenzae.
Applications:Suitable for use in ELISA and TLC Immunoblot.
Other applications have not been tested.
Recommended Dilution:ELISA: 1:200 Limit of detection ~50ng antigen
TLC: 1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：bovine
Grade：Serum
Purity：Serum.
Form：Supplied as a liquid.
Specificity：Recognizes bovine Asialo GM-2. No crossreactivity with other carbohydrate epitopes.
Isotype：IgG, IgM
Calc Applications Abbrev：E WB
Calc Crossreactivity：Bo
Immunogen：Bovine Asialo GM2 and Complete Freund’s adjuvant.
