A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera.
GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system.
It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS.
GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorylation and synaptic function.
Applications:Suitable for use in ELISA and TLC Immunoblot with peroxidase reaction.
Other applications have not been tested.
Recommended Dilutions:ELISA: 1:1600 (~50ng antigen optimal detection)TLC: 1:250Note: Dilution in PBS, pH 7.4, is recommended
Optimal dilutions to be determined by the researcher
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Grade:Serum
Purity:Serum
Form:Supplied as a liquid. No preservative added
Specificity:Recognizes Asialo GM-1. No crossreactivity with other carbohydrate epitopes.