84-1012-69　［取扱停止］Elongin A (Elongin-A, Ela1, EloA, Elongin 110kD Subunit, RNA Polymerase II Transcription Factor SIII Subunit A1, SIII, SIII p110, Transcription Elongation Factor B (SIII) Polypeptide 3 110kD, TCEB3, TCEB3A) 1mg　E2250

特徴

• Elongin A is a subunit of the transcription factor B (SIII) complex.
• The SIII complex is composed of elongins A/A2, B and C.
• It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units.
• Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.
• Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C.
• The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
• Applications:Suitable for use in ELISA, tumor suppression.
• Other applications have not been tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Suggested secondary antibodies:I1906IgY, Chicken Pab Rb x Ch I1906-10IgY, Chicken-HRP Rb x Ch I1906-12IgY, Chicken-FITC Rb x Ch I1906-14IgY, Chicken-AP Rb x Ch
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage, store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.