84-1011-15　Digitoxin 1ml　D8021

特徴

• Digitoxin is a purified cardiac glycoside similar in structure and function to Digoxin.
• Unlike Digoxin, Digitoxin is eliminated from the body via the liver and not the kidneys.
• Both drugs are used to treat various heart conditions.
• Cardiac glycosides bind to a site on the extracellular aspect of the a-subunit of the Na+/K+ ATPase pump in the membranes of heart cells (myocytes).
• This causes an increase in the level of sodium ions in the myocytes, which then leads to a rise in the level of calcium ions.
• Titer:40,000 tests/ml
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 6 months after receipt at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.